fbpx

REQUEST A CONSULTATION

Ready to contact us for a consultation about your condition and our medical services? The staff of our Global Patient Services is ready to help. Please select the appropriate button to get started.
search

Navigating Retinoblastoma: Expert Analysis by Prof. Didi Fabian

Text "SCIENCE DOSE" with a magnifying glass next to it zooming in on cells and viruses. Additional elements include a syringe, microscope, and blood cells.
Prof. Didi Fabian explored the complexity of retinoblastoma, a form of eye cancer impacting infants. His analysis covered genetic factors, treatment options, and the diverse global perspective on this condition.

Prof. Didi Fabian, a senior ocular oncologist at Sheba’s Goldschleger Eye Institute and Director of Sheba Global Ophthalmology, recently delved into retinoblastoma, an eye cancer primarily affecting young children. Emerging from genetic mutations within the retina, this condition is detectable and treatable, particularly in high-income regions where survival rates approach 100%. However, in areas with restricted healthcare access, global statistics and survival rates vary considerably.

Types of Retinoblastoma

Retinoblastoma can manifest in two main forms: germline and non-germline. Germline cases involve genetic mutations predisposing individuals to the disease, while non-germline cases occur spontaneously during a child’s development.

Familial vs. Non-Familial Cases

Familial retinoblastoma occurs in families with a history of the condition, signifying a hereditary predisposition. This form stems from inherited mutations in the RB1 gene, responsible for regulating cell growth. In contrast, non-familial cases develop without a family history, with mutations occurring spontaneously.

Treatment Options

Despite the complexity of retinoblastoma, advancements in diagnostics and treatments offer promising outcomes. From surgical interventions like enucleation for severe cases, to laser therapies such as photocoagulation for milder cases, modern medicine aims to eradicate these cancer cells while preserving vision and minimizing long-term effects.

Overall, retinoblastoma management emphasizes early detection and comprehensive treatment strategies to ensure optimal outcomes for affected children globally.

Related
Designing for Wellness: Place2Heal's Vision for Pediatric Care
At Sheba’s Edmond and Lily Safra Children’s Hospital, comforting and preparing young patients for medical procedures remains integral to their care. The formidable nature of…
Read More
Sheba's Legacy of Hope: Alexandra's Remarkable Road to Wellness
Last month, a celebratory atmosphere filled the halls of the Edmond and Lily Safra Children’s Hospital at Sheba. The occasion marked a significant milestone in…
Read More
Kerry's Fight Against Skin Cancer at Sheba
Looking back at 2020, 55-year-old Kerry Louise Matthews was in love with her life. Despite the pandemic, the UK native had just started on a…
Read More