Melanoma and Skin Cancer Treatment in Sheba
The Ella Lemelbaum Institute for Immuno-Oncology is dedicated to world-class melanoma treatment and continuous research into this widespread disease. Our top-tier staff, including clinicians, researchers, nursing staff, and support staff, are all dedicated to providing our patients and their families with integrative, total care.
To that end, the Ella Institute works in conjunction with some of the leading melanoma treatment centers around the globe, including the National Institutes of Health (NIH) in the United States.
We are proud to provide the absolute latest in melanoma treatment, including advanced immunotherapy techniques and the opportunity to participate in many ongoing clinical studies.
The Ella Institute exists due to the generosity of the Lemelbaum family, in memory of their daughter, Ella.
There our staff members
- Professor Jacob Shachter serves as the President of the Ella Institute. Prof. Shachter possesses expertise in melanoma and skin cancer treatment.
- Dr. Ronnie Shapira is one of Israel’s leading medical oncologists and is an Acting Director of the Ella Institute. Dr. Shapira received her MD from the Sackler School of Medicine at Tel Aviv University and completed her residency at Meir Medical Center.
- Nethanel (Nati) Asher, MD, is a senior physician, oncology specialist in the Ella Lemelbaum Institute of Immuno-Oncology at Sheba Medical Center.
- Dr. Michal Besser serves as the head of the Ella Institute’s Clinical Laboratory. Dr. Besser earned her PhD in immunology from the University of Munich in Germany and conducted her postdoctoral studies at the Weizmann Institute of Science in Israel.
Continuous research is conducted at the Ella Institute, with over 10 studies currently ongoing. Eligible patients receive treatment under the strictest ethical and safety standards.
Sheba Medical Center is a leader in tumor-infiltrating lymphocytes (TIL) immunotherapy. TIL is a promising treatment for patients with malignant metastatic melanoma, or melanoma that has spread beyond the outermost layers of the skin. These patients often have weakened immune systems and receive transfers of immune cells, with very encouraging results having been seen in clinical research. Sheba Medical Center has improved the TIL protocol and hopes to make use of it in other types of cancer in the future.
There are several various types of skin cancer, but squamous and basal cell skin cancers are the most frequently seen. Over 5 million people develop these types of cancer each year, more than 3 million of whom are Americans. These cancers typically form on areas of the skin that receive a lot of sun exposure, like the face, ears, forearms, and backs of the hands. They are usually highly treatable if discovered early enough.
Although melanoma makes up a small portion of all skin cancers, it is one of the most aggressive types of skin cancer. It develops in the melanocytes, the cells responsible for pigment production in the skin. Unfortunately, melanoma can form on any skin area, regardless of sun exposure. Again, melanoma can often be treated successfully if discovered soon enough.
The risk factors for skin cancer include:
- Sun and other ultraviolet light exposure
- Older age
- A family history of skin cancer
- Pale skin tone
- Having many moles on the skin
- A history of severe sunburns
Melanomas and other skin cancers are categorized according to several factors, such as stage 4 melanoma. These include how far the cancer has infiltrated into the skin, the size of the original tumor, and whether the cancer has spread to adjacent lymph nodes or distant areas of the body.
While early stage cancer always have the best prognoses, effective treatment is available for even metastatic, or widespread, skin cancers.
Some signs and symptoms of skin cancer include:
- Skin appearance changes, such as moles that change shape or color, new moles and other blemishes
- Scaly or bleeding skin areas
- Non-healing sores on the skin
- Soreness of skin areas
Skin cancers are typically surgically removed and then analyzed by a pathologist. A detailed pathologic examination is necessary to properly diagnose and stage 4 melanoma and other skin cancers.
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