What is Car-t therapy?
Car-T is a revolutionary, highly specialized and individualized treatment for leukemia, lymphoma and multiple myeloma, with clinical testing for other forms of cancer currently underway. Available at a limited number of cancer centers worldwide, we are pleased to offer Car-T therapy to patients from around the globe at Sheba Medical Center’s Hemato-Oncology Department.
Car-T therapy uses the patient’s white blood cells, which are genetically reprogrammed to kill cancer cells, enabling many patients who did not respond to other treatment methods to achieve remission. At Sheba, we have all the advanced facilities necessary for delivering the therapy from start to finish, including a dedicated laboratory to engineer the T-cells.
How does Car-T work?
While the modified T-cells grow in our laboratory, the patient receives chemotherapy to suppress their immune system. This creates a more efficient setting for the CAR T-cells to do their job and destroy malignant cells.
A significant benefit of the therapy is that it both stimulates T-cells to fight cancer and triggers their multiplication. Thus, after just one treatment, the cells continue to attack the tumor for months or even years. At Sheba, a global pioneer in the application of the therapy, more than 373 patients have already been treated.