Acute Lymphoblastic Leukemia (ALL) Treatment
ALL is a form of blood and bone marrow malignancy. Unfortunately, ALL tends to be aggressive and is sometimes seen in children. However, there is hope. Sheba Medical Cancer Center provides tailor-made medicine for our patients with state-of-the-art facilities, including our Bone Marrow Transplant Clinic and advanced therapy options. We also have a host of world-class experts who have studied and practiced at top cancer centers around the world to offer advanced acute lymphoblastic leukemia treatment for children and adults.
The exact cause is undetermined in the majority of ALL cases. Although research is making progress, we do not yet know the reasons why some people develop ALL while others do not. However, some risk factors have been identified. These include:
- Radiation exposure
- Family history of ALL
- Down syndrome
- Having undergone chemotherapy in the past
ALL is broadly classified by which types of lymphocytes are affected. B-cell ALL affects B lymphocytes, cells that are produced and mature in the bone marrow. B lymphocytes serve an immune role in antibody production. T-cell ALL affects T lymphocytes. While T lymphocytes are also produced in the bone marrow, these cells mature in the thymus, an organ of the lymphatic system. T lymphocytes are largely responsible for cell-mediated immunity. B-cell ALL makes up about 85% of all ALL cases, while T-cell ALL represents about 15%.
ALL is characterized by abnormal lymphocytes which cannot function properly. Moreover, these lymphocytes take space and resources away from other blood cells, such as red blood cells and platelets, leading to symptoms.
Signs and symptoms of ALL include:
- Unexplained weight loss
- Swollen and/or painful liver and spleen
- Flu-like symptoms, fevers, sweats, chills
Acute Lymphoblastic Leukemia Treatment in Israel
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