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Search Results for:"Hemato Oncology"

FAQ: Can retinoblastoma come back?

Retinoblastoma can sometimes come back after successful treatment, but this is rarely the case.

FAQ: Can adults get retinoblastoma?

Retinoblastoma most commonly affects children, but in extremely rare cases, it can also occur in adults.

FAQ: What are the stages of retinoblastoma?

As with other cancers, retinoblastoma is staged using the TNM system, starting at stage I, followed by stages II, III, and IV. The higher the stage, the more advanced the cancer.

FAQ: What are the symptoms of retinoblastoma?

One or more of the following symptoms can indicate an occurrence of retinoblastoma:

FAQ: What are the risk factors for retinoblastoma?

Whether or not someone is susceptible to developing retinoblastoma mostly depends on two factors. The first is age, as retinoblastoma primarily affects children under the age of three. The second risk factor is genetics, as approximately 41% of children diagnosed with retinoblastoma have inherited the gene that causes the disease (RB1) from their parents.

FAQ: What causes retinoblastoma?

Retinoblastoma is caused by a genetic mutation in the RB1 gene, which causes eye cells to grow uncontrollably, ultimately causing a tumor to form.

FAQ: What is retinoblastoma?

Retinoblastoma is a type of eye cancer that primarily affects children and develops in the retina, the back part of the eye.

FAQ: How are CAR T-cells engineered?

CAR T-cells are engineered through a complex laboratory process. First, T-cells are collected from the patient’s blood through leukapheresis. These T-cells are then genetically modified to express chimeric antigen receptors (CARs) on their surface. The genetic modification involves introducing specific genes into the T-cells using viral vectors. These genes encode the CAR proteins, which consist […]

FAQ: What are the advantages of allogeneic CAR T-cells?

Allogeneic CAR T-cells are derived from a healthy donor’s T-cells rather than the patient’s own cells, which offers several advantages. One key benefit is that allogeneic CAR T-cells can be manufactured in large quantities and stored for off-the-shelf use. This potentially reduces the time required for treatment and can be readily available for patients. Additionally, […]