FAQ: How long do CAR T-cells stay in the body?

The duration of CAR T-cells’ presence in the body varies from patient to patient and depends on multiple factors. Typically, infused CAR T-cells can persist in the body for months to years after treatment. However, their persistence may decline over time. Despite this, some CAR T-cells may remain in the body as memory T-cells, providing the potential for long-term surveillance against cancer recurrence. The duration of CAR T-cell persistence and its efficacy may influence the need for additional treatments or interventions over time.