FAQ: How do CAR T-cells work?

CAR T-cells work by recognizing and targeting specific cancer cells in the body. They are engineered in a laboratory to express chimeric antigen receptors (CARs) on their surface. These CARs allow the T-cells to bind to cancer cells that express the corresponding antigen. Once the CAR T-cells are infused back into the patient, they recognize the cancer cells and initiate an immune response against them. This response involves the activation and proliferation of the CAR T-cells, leading to the destruction of cancer cells. CAR T-cell therapy harnesses the power of the patient’s own immune system to fight cancer in a highly targeted and potent manner.