CAR T-Cell Therapy for Multiple Myeloma

CAR T-cell therapy is an innovative procedure that uses your own immune system to seek and destroy cancerous cells. The CAR T-cell process begins with the patient’s blood being drawn. White blood cells (specifically, T-cells, an essential part of the immune system) are then separated from the rest of the blood using advanced technology. The white blood cells are subsequently sent to a specialized laboratory, where they are engineered to produce specific chimeric antigen receptors (CARs) on their surface. These CAR T-cells are then injected back into the patient’s bloodstream, where the new CARs can help them latch on to an antigen on tumor cells – significantly increasing their ability to effectively hunt down and destroy malignancies.

While the treatment was limited to acute lymphocytic leukemia, non-Hodgkin’s lymphoma, and acute myelogenous leukemia patients until recently, CAR T-cell therapy is now approved for the treatment of multiple myeloma.

Unfortunately, as a cutting-edge treatment, CAR T-cell therapy is only available at a handful of medical institutions worldwide, and tends to be an expensive and prolonged process.

One of the 10 best hospitals in the world according to Newsweek magazine, Sheba is dedicated to providing patients with world-class medical care. At Sheba Medical Center, we boast all of the advanced facilities necessary for delivering CAR T-cell therapy from start to finish: including a dedicated laboratory to engineer the T-cells. This shortens the treatment process from many months to no more than 10 weeks.

Advantages of treatment at Sheba Medical Center include:

• As a government institution, we have no hidden costs, and our fees are transparent. Although we offer advanced treatments available only in select medical institutions worldwide, our prices are affordable.
• Sheba treats each patient as a unique individual, personalizing every therapy program.
• Sheba’s 360-degree care approach to every patient means that our professionals will assist you with arranging medical record reviews, travel, visas, accommodations, and language interpretation as needed.
• Sheba has full accreditation from the Joint Commission International (JCI), the premier international healthcare accrediting group.
• Our physicians are actively involved in the latest research and application of progressive treatments.
• Sheba’s extensive experience with CAR T-cell therapy speaks louder than words. Under the expertise of Prof. Arnon Nagler, Director of the Hemato-Oncology Division and a world-renowned specialist in the field, we have provided over 220 patients with CAR T-cell therapy.
• Convenient on-site CAR T-cell care: We offer all of the required services for CAR T-cell therapy under one roof, including blood collection, chemotherapy, a genetic engineering laboratory, T-cell injections, and patient monitoring, resulting in an efficient and expedited treatment.
• Multidisciplinary medicine: at Sheba, specialists from various departments collaborate to create a holistic treatment plan.