Esophageal Cancer Treatment in Israel
Esophageal Cancer Treatment in Israel
The esophagus is a hollow tube that connects your throat to your stomach. After you swallow, food moves through this long tube to the stomach, where it is digested. Esophageal cancer is the sixth most common cause of cancer deaths worldwide, and it can develop at any point along the esophagus.
At Sheba Medical Center, our multidisciplinary physicians – including oncologists, gastroenterologists, imaging specialists, surgeons, radiologists, and dietitians – work together to treat every patient diagnosed with esophageal cancer. Full collaboration between different hospital divisions enables us to design individualized, comprehensive, and holistic treatment plans. We are constantly involved in clinical studies to explore new cancer therapies, and our expert team meets with every patient to review the best options for esophageal cancer treatment in Israel.

Stages of Esophageal Cancer
- Squamous cell carcinoma, which develops in the cells lining the esophageal mucosa.
- Adenocarcinoma, which develops in the cells of the subcutaneous layer of the esophagus.
| Stage 0:
Abnormal cells, not yet cancer, are found only in the esophageal lining.
| Stage 1:
Cancer cells are found in the esophageal lining (in the subcutaneous layer and the muscle).
| Stage 2:
The tumor has reached the outer wall of the esophagus or the muscle layer. Also, the cancer may have spread to one or two adjacent lymph nodes.
| Stage 3:
The cancer has penetrated deeper into the inner muscle layer or into the connective tissue wall of the esophagus. It may also have spread to multiple adjacent lymph nodes or to a nearby organ (e.g., diaphragm)
| Stage 4:
The cancer has spread to other organs in the body (metastases), such as the abdominal cavity, liver and lungs, and lymph nodes located far from the esophagus. This is the most advanced stage.
Diagnosis
Sheba’s doctors will review your symptoms and medical history and perform a physical exam to diagnose esophageal cancer. To confirm your diagnosis, stage the disease, and plan the best esophageal cancer treatment in Israel, various tests and X-rays may also be performed, including:
- Barium swallow X-ray: You drink a liquid that coats the esophagus, making it appear more clearly on the X-ray
- Endoscopy: An endoscope (a thin, lighted tube), is placed down your throat into your esophagus. Endoscopic ultrasound (EUS) may also be done, which uses sound waves to obtain additional information about tumor involvement in adjacent tissues
- MRI (magnetic resonance imaging): A magnetic field and radio waves are used to generate a detailed 3D image of the tissues
- CT scan (computerized tomography): This procedure produces 3D images of the tissues that provide precise information on the size, location, and shape of the tumor; it can also locate cancerous lymph nodes
- PET scan: With positron emission tomography, a radioactive substance is injected into the body, where it binds to tissues that have a faster metabolic rate – such as malignant tumors; the images created show how this substance is dispersed in the body, thereby helping to diagnose the precise location and spread of the tumor
- Biopsy: During an endoscopy (sometimes with the guidance of an ultrasound or CT), the doctor can excise cells or tissue for further examination under a microscope

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Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone.
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