TIL Immunotherapy
Treatment for Metastatic Melanoma in Israel

Tumor-infiltrating lymphocytes (TIL) immunotherapy is a modern treatment for patients with advanced stage metastatic melanoma who have experienced little or no benefit from conventional therapies. About 50% of these patients show improvement with TIL and approximately 25% of patients are cured of their melanoma.

TIL is offered at only a few medical institutes worldwide, and we are proud to provide this innovative treatment for patients from the UAE at the Ella Lemelbaum Institute for Immuno-Oncology at Sheba Medical Center in Israel. Our campus is located closer to the UAE than Europe and the United States, and the cost of treatment is lower.

What is
TIL Immunotherapy?

TILs, or tumor-infiltrating lymphocytes, are special immune system cells (T cells) that are naturally present inside some tumors.

TIL immunotherapy consists of collecting TILs from a tumor during a biopsy, or surgical resection, and growing them to very large numbers in a laboratory with interleukin-2 (IL-2), a protein that promotes rapid TIL growth. Once successfully grown to billions in number, the TILs are infused back into the patient, where they actively attack cancer cells.

Your immune system is thus able to produce a stronger, more focused response against the tumor cells.

What Conditions Do We Treat with TIL Immunotherapy at Sheba?

At present, TIL immunotherapy is offered to patients from the UAE who have advanced metastatic melanoma that has not responded to conventional cancer treatments.

Why Choose Sheba
for TIL Immunotherapy?

On the Frontline We have been actively engaged with TIL research, collaborating closely with the National Institutes of Health (NIH) in the United States.

Experienced Medical Experts Our staff features many of the world’s leading, highly experienced TIL specialists.

Top Notch Facility You will receive treatment at the Ella Lemelbaum Institute for Immuno-Oncology, a modern; facility devoted entirely to cancer immunotherapy research and treatment.

Supportive Experience A personal coordinator from our International Medical Tourism Division will assist you throughout your entire time at Sheba, including helping you with travel arrangements, translation, family accommodations and many other needs

Affordable Treatment The fees at Sheba are transparent and affordable, with no hidden costs

Internationally Recognized We have full accreditation from the Joint Commission International (JCI), the foremost healthcare center accreditation authority

Comprehensive Care You will have access not only to TIL treatments, but to a broad range of specialized cancer therapies

Why Come to Sheba
from the UAE?

Presently, the UAE sends many complex patient cases to other countries, and now, Sheba offers a treatment option for metastatic melanoma that is closer than Europe and less expensive than the United States. Many members of the medical staff also speak Arabic, creating a comfortable atmosphere – like a home away from home.

TIL immunotherapy in Israel provides patients from the UAE with custom designed advanced treatment administered by world-renowned cancer specialists. Not only is Sheba the largest, most comprehensive hospital in the Middle East, but for the past two years it was ranked by Newsweek as one of the top 10 hospitals in the world. As a leading international force in medicine and biotechnological innovation, Sheba offers many treatments and technologies that are unavailable elsewhere. Presidents, VIPs and top-level executives regularly choose Sheba for medical treatment.


Joining forces to advance patient care:

Sheba Medical Center and APEX National Investment, based in Abu Dhabi, recently signed a memorandum of agreement, laying the groundwork for medical tourism, medical training and digital healthcare innovation. To encourage startups, Sheba and APEX will set up a collaborative healthcare hub for the UAE modeled after the ARC Innovation Center on Sheba’s campus in Israel.

Patients Share
How TIL Immunotherapy Saved Mike’s Life

“We think choosing TIL at Sheba was undoubtedly the best decision. That is what saved my husband.”

Mike and Michaela Herstig, married for 40 years and living in Bangkok, were terrified by Mike’s diagnosis of stage 4 metastatic melanoma. Unwilling to give up, Michaela researched the best available treatment options, which led her to Sheba Medical Center in Israel. Innovative TIL immunotherapy was recommended as a highly effective treatment, and Mike and Michaela decided to give it a try.

The Director

Jacob Schachter, MD, PhD

Director Emeritus, the Ella Lemelbaum Institute for Immuno-Oncology
Deputy Director of the Oncology Division, The Sheba Medical Center

Prof. Schachter is one of the most prominent oncologists practicing in the field of melanoma in Israel. In 2004, he founded the Ella Institute, which offers innovative treatments for melanoma patients, including innovative TIL immunotherapy, available today only at a few cancer centers worldwide. Prof. Schachter is involved in planning and implementing many researches in melanoma treatment, and he has published more than 50 scientific papers on melanoma and tumor immunology

Holistic healing at sheba

When providing TIL immunotherapy in Israel, we consider all aspects of each patient’s overall wellness and quality of life, including physical, emotional, and social needs. We aim to create the most customized, comfortable and efficient experience possible, with all-inclusive services, such as psychology, social services, beneficial complementary medicine, and palliative care offered under one roof on our vast campus. Every patient is also assigned a personal medical coordinator from the International Medical Tourism Division, who provides assistance throughout every step of the treatment.

Sheba –
Ranked In ThE TOP TEN
Best Hospitals Worldwide

Sheba Medical Center sets the standard for excellence in patient-focused care. Recently, Newsweek included Sheba on their prestigious list of the Top Ten Best Hospitals Worldwide. This endorsement recognizes Sheba as a leading force in medical science and biotechnological innovation – maximizing the latest technologies while always providing holistic, outstanding healthcare. Sheba is strongly committed to delivering personalized, expert medicine to everyone from all over the world.


The 10 Best Hospitals in the World

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