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TIL Immunotherapy Treatment for Metastatic Melanoma in Israel

Tumor-infiltrating lymphocytes (TIL) immunotherapy is a modern treatment for patients with advanced stage metastatic melanoma who have experienced little or no benefit from conventional therapies. About 50% of these patients show improvement with TIL and approximately 25% of patients are cured of their melanoma.

TIL is offered at only a few medical institutes worldwide, and we are proud to provide this innovative treatment for patients from the UAE at the Ella Lemelbaum Institute for Immuno-Oncology at Sheba Medical Center in Israel. Our campus is located closer to the UAE than Europe and the United States, and the cost of treatment is lower.

Sheba Medical Center is one of the few institutions where patients can receive CAR T-cell Therapy for Multiple Myeloma

What Is Til Immunotherapy

TILs, or tumor-infiltrating lymphocytes, are special immune system cells (T cells) that are naturally present inside some tumors.

TIL immunotherapy consists of collecting TILs from a tumor during a biopsy, or surgical resection, and growing them to very large numbers in a laboratory with interleukin-2 (IL-2), a protein that promotes rapid TIL growth. Once successfully grown to billions in number, the TILs are infused back into the patient, where they actively attack cancer cells.

Your immune system is thus able to produce a stronger, more focused response against the tumor cells.

TIL Immunotherapy Treatment for Advanced Melanoma in Israel

What Conditions Do We Treat with TIL Immunotherapy at Sheba?

At present, TIL immunotherapy is offered to patients from the UAE who have advanced metastatic melanoma that has not responded to conventional cancer treatments.

Why Choose Sheba for TIL Immunotherapy

TIL is available in only a very few countries. Sheba Medical Center in Israel is a great choice for your TIL Immunotherapy treatment destination for several reasons:

On the Frontline

We have been actively engaged with TIL research, collaborating closely with the National Institutes of Health (NIH) in the United States.

Affordable Treatment

The fees at Sheba are transparent and affordable, with no hidden costs

Experienced Medical Experts

Our staff features many of the world’s leading, highly experienced TIL specialists.

Internationally Recognized

We have full accreditation from the Joint Commission International (JCI), the foremost healthcare center accreditation authority

Top Notch Facility

You will receive treatment at the Ella Lemelbaum Institute for Immuno-Oncology, a modern; facility devoted entirely to cancer immunotherapy research and treatment.

Comprehensive Care

You will have access not only to TIL treatments, but to a broad range of specialized cancer therapies

Supportive Experience

A personal coordinator from our Global Patient Services team will assist you throughout your entire time at Sheba, including helping you with travel arrangements, translation, family accommodations and many other needs

Why Come to Sheba from the UAE?

Presently, the UAE sends many complex patient cases to other countries, and now, Sheba offers a treatment option for metastatic melanoma that is closer than Europe and less expensive than the United States. Many members of the medical staff also speak Arabic, creating a comfortable atmosphere – like a home away from home.

TIL immunotherapy in Israel provides patients from the UAE with custom designed advanced treatment administered by world-renowned cancer specialists. Not only is Sheba the largest, most comprehensive hospital in the Middle East, but for the past two years it was ranked by Newsweek as one of the top 10 hospitals in the world. As a leading international force in medicine and biotechnological innovation, Sheba offers many treatments and technologies that are unavailable elsewhere. Presidents, VIPs and top-level executives regularly choose Sheba for medical treatment.

Joining forces to advance patient care:

Sheba Medical Center and APEX National Investment, based in Abu Dhabi, recently signed a memorandum of agreement, laying the groundwork for medical tourism, medical training and digital healthcare innovation. To encourage startups, Sheba and APEX will set up a collaborative healthcare hub for the UAE modeled after the ARC Innovation Center on Sheba’s campus in Israel.

Patients Share

How TIL Immunotherapy Saved Mike’s Life

“We think choosing TIL at Sheba was undoubtedly the best decision. That is what saved my husband.”

Mike and Michaela Herstig, married for 40 years and living in Bangkok, were terrified by Mike’s diagnosis of stage 4 metastatic melanoma. Unwilling to give up, Michaela researched the best available treatment options, which led her to Sheba Medical Center in Israel. Innovative TIL immunotherapy was recommended as a highly effective treatment, and Mike and Michaela decided to give it a try.

Read Mike’s story

The Director

Ronnie Shapira

Ronnie Shapira, MD

Director of the Ella Institute for Immuno-Oncology

Ronnie Shapira, MD. is an Oncologist at The Ella Institute for Immuno-Oncology which is a center of knowledge and excellence, implementing some of the world’s most advanced and unique treatment methodologies for melanoma and skin cancer, operating within the Sheba Medical Center. She is a Head of Onco-Gynecological cancer unit, leading the treatment of gynecological malignancies at the Oncology Institute.

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Holistic healing at Sheba

When providing TIL immunotherapy in Israel, we consider all aspects of each patient’s overall wellness and quality of life, including physical, emotional, and social needs. We aim to create the most customized, comfortable and efficient experience possible, with all-inclusive services, such as psychology, social services, beneficial complementary medicine, and palliative care offered under one roof on our vast campus. Every patient is also assigned a personal medical coordinator from Global patient services, who provides assistance throughout every step of the treatment.

Sheba Medical Center Transforming Healthcare and Biomedical Innovation

Standing at the forefront of clinical research, innovation, and patient care, Sheba Medical Center, the largest hospital in the Middle East, continues to set the standard for international excellence. For the fifth consecutive year, Newsweek ranked Sheba as one of the world’s best hospitals, as well as listing the medical center as one of the best smart hospitals and a leader in gastroenterology, neurology, and cardiology. Committed to advancing patient care and transforming healthcare worldwide, Sheba continually pushes boundaries in research and clinical care.

Request a consultation

Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone.

We welcome all cases, including the rarest and the most challenging. Our medical teams collaborate to provide the best possible health outcomes. From your initial inquiry through the long-term follow-up care, we are here for you.

Request a consultation and a Sheba Case Manager will contact you shortly: