TIL Immunotherapy Treatment for Metastatic Melanoma in Israel
Tumor-infiltrating lymphocytes (TIL) immunotherapy is a modern treatment for patients with advanced stage metastatic melanoma who have experienced little or no benefit from conventional therapies. About 50% of these patients show improvement with TIL and approximately 25% of patients are cured of their melanoma.
TIL is offered at only a few medical institutes worldwide, and we are proud to provide this innovative treatment for patients from the UAE at the Ella Lemelbaum Institute for Immuno-Oncology at Sheba Medical Center in Israel. Our campus is located closer to the UAE than Europe and the United States, and the cost of treatment is lower.

What Is Til Immunotherapy
TILs, or tumor-infiltrating lymphocytes, are special immune system cells (T cells) that are naturally present inside some tumors.
TIL immunotherapy consists of collecting TILs from a tumor during a biopsy, or surgical resection, and growing them to very large numbers in a laboratory with interleukin-2 (IL-2), a protein that promotes rapid TIL growth. Once successfully grown to billions in number, the TILs are infused back into the patient, where they actively attack cancer cells.
Your immune system is thus able to produce a stronger, more focused response against the tumor cells.

Why Choose Sheba for TIL Immunotherapy
TIL is available in only a very few countries. Sheba Medical Center in Israel is a great choice for your TIL Immunotherapy treatment destination for several reasons:
On the Frontline
We have been actively engaged with TIL research, collaborating closely with the National Institutes of Health (NIH) in the United States.
Affordable Treatment
The fees at Sheba are transparent and affordable, with no hidden costs
Experienced Medical Experts
Our staff features many of the world’s leading, highly experienced TIL specialists.
Internationally Recognized
We have full accreditation from the Joint Commission International (JCI), the foremost healthcare center accreditation authority
Top Notch Facility
You will receive treatment at the Ella Lemelbaum Institute for Immuno-Oncology, a modern; facility devoted entirely to cancer immunotherapy research and treatment.
Comprehensive Care
You will have access not only to TIL treatments, but to a broad range of specialized cancer therapies
Supportive Experience
A personal coordinator from our Global Patient Services team will assist you throughout your entire time at Sheba, including helping you with travel arrangements, translation, family accommodations and many other needs
Patients Share
“We think choosing TIL at Sheba was undoubtedly the best decision. That is what saved my husband.”
Mike and Michaela Herstig, married for 40 years and living in Bangkok, were terrified by Mike’s diagnosis of stage 4 metastatic melanoma. Unwilling to give up, Michaela researched the best available treatment options, which led her to Sheba Medical Center in Israel. Innovative TIL immunotherapy was recommended as a highly effective treatment, and Mike and Michaela decided to give it a try.
The Director

Jacob Schachter, MD, PhD
Director Emeritus, the Ella Lemelbaum Institute for Immuno-Oncology Deputy Director of the Oncology Division, The Sheba Medical Center
Prof. Schachter is one of the most prominent oncologists practicing in the field of melanoma in Israel. In 2004, he founded the Ella Institute, which offers innovative treatments for melanoma patients, including innovative TIL immunotherapy, available today only at a few cancer centers worldwide. Prof. Schachter is involved in planning and implementing many researches in melanoma treatment, and he has published more than 50 scientific papers on melanoma and tumor immunology
Read MoreHolistic healing at Sheba
When providing TIL immunotherapy in Israel, we consider all aspects of each patient’s overall wellness and quality of life, including physical, emotional, and social needs. We aim to create the most customized, comfortable and efficient experience possible, with all-inclusive services, such as psychology, social services, beneficial complementary medicine, and palliative care offered under one roof on our vast campus. Every patient is also assigned a personal medical coordinator from Global patient services, who provides assistance throughout every step of the treatment.
Sheba Medical Center Transforming Healthcare and Biomedical Innovation

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Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone.
We welcome all cases, including the rarest and the most challenging. Our medical teams collaborate to provide the best possible health outcomes. From your initial inquiry through the long-term follow-up care, we are here for you.
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