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Primary Liver Cancer (Hepatocellular Carcinoma) Treatment in Israel

Primary liver cancer, known as hepatocellular carcinoma, originates in the liver cells and develops within the liver. There are several types of primary liver cancer, and treatment must be personalized to achieve optimal results. At The Center for Liver Diseases at Sheba Medical Center in Israel, top-notch specialists provide cutting-edge care for every patient. Using a range of modern technologies, our multidisciplinary team evaluates each case to design customized, comprehensive therapies.

Sheba Medical Center

What Treatments Does Sheba Offer for Primary Liver Cancer?

Sheba is pleased to offer the newest effective therapies to treat hepatocellular carcinoma. Doctors from various medical departments will evaluate your condition thoroughly and collaborate to customize an integrative treatment to meet your unique needs. Treatment options at Sheba include:


a partial, selective resection is the main treatment for primary liver cancer.


this breakthrough treatment is performed by inserting a needle into the center of the tumor, which heats and destroys cancer cells. The process is local and direct, so damage to nearby tissue is minimized.

Transarterial Chemoembolization (TACE):

chemotherapy drugs are administered via a catheter that is inserted into the artery of the liver, and then the artery is blocked – leading to necrosis of the cancer. Another version of TACE involves injecting beads that are filled with chemotherapy drugs into the liver artery.

Radioembolization – Selective Internal Radiation Therapy (SIRT):

small glass pellets coated with a radioactive substance are injected into the hepatic artery, enabling localized irradiation and necrosis of the tumor, while avoiding damage to surrounding healthy tissue.

Biological treatments:

growth inhibitors, administered as a one-time oral pill, affect the tumor’s ability to develop. This treatment is generally used for patients with advanced metastatic primary liver cancer.

Primary Liver Cancer

Why Come to Sheba For Primary Liver Cancer Treatment in Israel?

Extensive Experience

we treat approximately 6,500 patients annually at our Center for Liver Diseases, which is one of the largest centers in Israel

World-class Medicine

our hospital has been awarded full accreditation from the Joint Commission International (JCI), the prestigious gold standard for healthcare

Multidisciplinary Experts

doctors from many departments collaborate to personalize and optimize your integrative care

Cutting-edge Therapies

we implement the latest research-based, advanced clinical procedures.

All-inclusive Care

we offer all the diagnostics and treatments that you need conveniently on our comprehensive campus

Patient-centric Comfort

we care about each individual’s experience, and a personal medical coordinator from Global patient services will help you with every detail

Sheba Medical Center A Recognized Leader in Global Healthcare

Sheba Medical Center, the largest and most prominent medical center in the Middle East, continues to set the standard for excellence in care. For the fifth year in a row, Newsweek included Sheba on their list of the world’s best hospitals, in addition to naming it as one of the best smart hospitals and a leader in gastroenterology, neurology, and cardiology. Sheba’s vision for global healthcare combines clinical excellence and medical innovation alongside international collaboration, and we employ these powerful resources to help patients worldwide.

Meet the Department Manager and Our Doctors

Einat Shacham-Shmueli

Einat Shacham-Shmueli, MD

Senior Oncologist, Gastrointestinal Clinic at the Cancer Center

Dr. Shacham-Shmueli is involved in specialized research in the fields of gastrointestinal malignancies, cancer, and genetics, and she has published 25 original scientific articles.

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Eylon Lahat, MD

Senior Physician, Department of Liver and Pancreas Surgery

He is also a member of the clinical staff at the Liver Transplant and Liver and Pancreas Surgery Department at Henri Mondor Hospital in France and has published widely in medical journals.

Daniel Azoulay

Daniel Azoulay, MD

Senior Surgeon, Center for Liver Diseases

Prof. Azoulay is one of the world’s leading surgeons in the field of complex liver surgeries and liver transplants, having performed more than 1,500 liver transplants to date. He is highly experienced in surgical shunts, liver ablation, in situ hypothermic perfusion of the liver, and split liver transplantation. Dr. Azoulay has published more than 400 articles in international medical literature.

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Gil Golan, MD

Senior Physician, Division of Diagnostic and Interventional Imaging

Specializing in a range of medical conditions, Dr. Golan’s main interests and areas of research include invasive gynecologic and obstetric treatments (such as endovascular therapy of the placenta and the treatment of fibroids), endovascular treatment of varicose veins, and endovascular treatments in oncology patients.

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Holistic Healthcare We Care About Your Quality of Life

At Sheba, we understand that a diagnosis of primary liver cancer has ramifications that reach far beyond your liver. So when we custom tailor your treatment, we pay attention to much more than your disease. Our compassionate team is dedicated to practicing holistic medicine that considers your overall well-being, including the physical and emotional aspects. A premier team of on-site specialists – hepatologists, gastroenterologists, hepatobiliary surgeons, radiologists, oncologists, psychologists, and supportive social services staff – will work together to maximize your quality of life.

Request a consultation

Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone.

We welcome all cases, including the rarest and the most challenging. Our medical teams collaborate to provide the best possible health outcomes. From your initial inquiry through the long-term follow-up care, we are here for you.

Request a consultation and a Sheba Case Manager will contact you shortly: