Does multiple myeloma cause bone fractures?
Yes, bone involvement is common in multiple myeloma. Myeloma cells release substances that activate osteoclasts, leading to increased bone resorption. This results in weakened bones, increasing the risk for fractures even with minimal trauma. The most common sites are the spine, ribs and long bones. Proper monitoring using imaging techniques and treatments like bisphosphonates, which help strengthen bones, can reduce the risk of fractures.