Does multiple myeloma cause back pain?
Multiple myeloma often involves the bones, particularly the spine, leading to significant back pain for many patients. This pain can be due to lytic lesions (areas of bone destruction), vertebral fractures or spinal nerve compression. Myeloma cells produce substances that stimulate osteoclasts (cells that break down bone), leading to weakened bones and fractures. Proper diagnosis using imaging like MRIs or X-rays is vital. Pain management, radiation therapy and even surgery may be required to treat or stabilize the affected areas.