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Patient Knowledge Base

Does multiple myeloma affect the brain?

Direct involvement of the brain by multiple myeloma is rare. However, complications or indirect effects associated with the disease or its treatment can impact the nervous system and brain. Hypercalcemia, a possible complication of myeloma, can lead to confusion, depression or other neurological symptoms. Some treatments might also have side effects like peripheral neuropathy or “chemo brain,” a condition characterized by cognitive changes during or after chemotherapy. It’s crucial for patients to communicate any neurological symptoms to their doctor for appropriate management and care.

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