Do myeloma cells produce antibodies?
Yes, myeloma cells produce a type of antibody called monoclonal protein or M-protein. In a healthy individual, plasma cells (from which myeloma cells derive) produce antibodies in response to infections. However, in multiple myeloma, the malignant plasma cells produce an abnormal amount of a single type of antibody, which doesn’t have a protective function. This M-protein can be detected in the blood or urine and is often used to diagnose and monitor the disease.