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Patient Knowledge Base

Can multiple myeloma be mistaken for osteoporosis?

Both osteoporosis and multiple myeloma can lead to decreased bone density and an increased risk of fractures. However, they arise from different pathologies: osteoporosis from decreased bone mass and myeloma from malignant plasma cell proliferation in the bone marrow. While a bone density test might show reduced density in both conditions, specific patterns like lytic lesions are more indicative of myeloma. Blood tests, clinical evaluations and imaging scans can help distinguish between them. Ensuring an accurate diagnosis is paramount, as the treatments and prognoses for these conditions differ substantially.

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