Does CAR T-cell therapy have any side effects?

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Almost half of all patients who undergo CAR T-cell therapy experience side effects, typically within the first few weeks after treatment. Many of these side effects can be managed effectively with medication.

The most common side effects include:

  • Cytokine release syndrome, which involves high fever, chills, low blood pressure, muscle or joint pain, shortness of breath, and a fast heart rate
  • Neurologic difficulties
  • Anemia (low red blood cell count)
  • Neutropenia (low white blood cell count)
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