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Ocular Melanoma Treatment in Israel

Melanoma, a type of cancer that occurs in the cells that produce melanin, can develop in the eye – most commonly in the uvea, the middle layer of the eye. Our staff at the Goldschleger Eye Institute and the Ella Lemelbaum Institute for Immuno-oncology at Sheba Medical Center offers a range of specialized medical and surgical services for eye disease. Malignant eye tumors are rare, and our multidisciplinary physicians are experienced leaders in their fields, providing the latest ocular melanoma treatment in Israel. Our goal is to save lives, preserve the eye, and protect against vision loss. We embrace the most progressive, personalized methods, such as brachytherapy, to achieve our goals.

Ocular Melanoma Treatment in Israel and retinoblastoma treatment

Treatments at Sheba

We treat patients of all ages with a wide range of treatment methods, custom-tailored for each individual’s condition. Therapies include:

  • Brachytherapy – Radiation therapy
  • TIL immunotherapy
  • Surgery
  • Laser treatment

Special Technologies Offered at Sheba


Ocular tumor cells respond well to radiation, but conventional radiotherapy can damage many healthy cells in the eye, leading to vision loss. Brachytherapy (also known as plaque therapy) is a unique, revolutionary treatment method, and Sheba is one of only a few clinics worldwide to administer it.

This therapy uses radioactive iodine 125 plaques that are placed directly on the eye surface, right above the base of the tumor. Using advanced computer software, the size of the plaque is adjusted precisely and customized to be as effective as possible for irradiating the individual’s eye tumor (with consideration for the size and shape of the tumor). This method allows controlled and direct irradiation, without exposing healthy retinal areas to excess radiation. As a result, damage to eyesight is prevented.

TIL Immunotherapy

TIL (tumor-infiltrating lymphocytes) immunotherapy is used as a treatment for metastatic melanoma. This cutting-edge treatment involves drastically increasing the number of elite cancer-killing lymphocytes in your body that target and attack malignant cells. Patients with uveal melanoma may develop secondary tumors in the future, and if the melanoma metastasizes, TIL immunotherapy can be an effective treatment option.

Ocular Melanoma Treatment in Israel and retinoblastoma treatment

Meet the Director

Vicktoria Vishnevskia-Dai

Vicktoria Vishnevskia-Dai, MD

Senior Ophthalmologist, Director of the Ocular Oncology and Inflammatory Eye Diseases Service Consultant for the Pediatric Oncology Department, Oncology Institute and Immunology Institute

Dr. Vishnevskia-Dai received her medical degree from the Sackler Faculty of Medicine, Tel Aviv University, and she completed a Clinical and Surgical Fellowship in Ocular Oncology at the Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA. From 1999-2003, Dr. Vishnevskia-Dai was an instructor in the course of Ocular Diseases Among the Aging Population, at the nursing school of Assaf Harofeh Medical Center.

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Ido Didi Fabian

Ido Didi Fabian, MD

Consultant Ocular Oncologist, Goldschleger Eye Research Institute

Dr. Fabian runs the ocular oncology laboratory at the Goldschleger Eye Institute at Sheba, where he is actively involved in researching innovative treatments for ocular tumors. He has a particular interest and expertise in treating retinoblastoma, ocular lymphoma, and conjunctival melanoma. Dr. Fabian is the initiator and principal investigator of the Global Retinoblastoma 2017 study, and he is a member of Sight for All, an Australian nonprofit that focuses on ocular oncology training in South East Asia. He is also a member of the Retinoblastoma-Network; in this role, he trains local doctors from Sub-Saharan East Africa. Dr. Fabian has published dozens of scientific articles in international journals.

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Roberto Spiegelmann

Roberto Spiegelmann, MD

Senior Staff Neurosurgeon, Department of Neurosurgery Head, Stereotactic Radiosurgery Unit and Functional Neurosurgery Service

Dr. Spiegelmann founded the first radiosurgery facility in the Middle East at Sheba, in December, 1992. This linear accelerator Radiosurgery Unit has since treated over 5,000 patients. Dr. Spiegelmann is very active in the field of radiosurgery, both nationally and internationally. In Israel, he pioneered the combined approach of microsurgery and radiosurgery improve the management of complex clinical situations in patients with metastatic brain disease, acoustic neurinomas, and meningiomas. As the first functional neurosurgeon in the country, Dr Spiegelmann introduced many advanced therapies to Israel.

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Why Choose Sheba for Ocular Melanoma Treatment?

World-class Team

the staff of the Goldschleger Eye Institute includes more than 50 eye specialists and residents, 30 highly qualified nurses, and experienced medical technicians

Extensive Experience

Sheba’s Eye Institute, the largest Ophthalmology Department in Israel, performs approximately 3,800 procedures yearly

Frontline Treatments

we are one of only a few hospitals in the world to offer cutting-edge brachytherapy for ocular melanoma

Internationally Renowned

we were listed in the Top 10 Hospitals in the World by Newsweek, and we are fully accredited by the Joint Commission International (JC), the gold standard for quality and safety in healthcare

Comprehensive Care

all diagnoses and treatments are provided conveniently under one roof on our all-inclusive campus

Supportive Care

a personal medical coordinator from Global patient services will help with all arrangements, including travel, accommodations, and communication in your language

Sheba – Ranked In The Top Ten Best Hospitals Worldwide

Sheba Medical Center sets the standard for excellence in patient-focused care. Recently, Newsweek included Sheba on their prestigious list of the Top Ten Best Hospitals Worldwide. This endorsement recognizes Sheba as a leading force in medical science and biotechnological innovation – maximizing the latest technologies while always providing holistic, outstanding healthcare. Sheba is strongly committed to delivering personalized, expert medicine to everyone from all over the world.

Holistic Healthcare for Cancer

When we treat patients with ocular melanoma, we focus on more than the eye disease. Sheba specialists practice medicine with a holistic, individualized approach – using professional expertise to custom-design the most suitable treatment program for each patient. Therapies include a range of support services, such as social services, rehabilitation therapy, and psychologists. We believe that the success of treating a patient with oncological eye disease is based on the collaboration of a compassionate, multidisciplinary team.

Request a consultation

Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone.

We welcome all cases, including the rarest and the most challenging. Our medical teams collaborate to provide the best possible health outcomes. From your initial inquiry through the long-term follow-up care, we are here for you.

Request a consultation and a Sheba Case Manager will contact you shortly: