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Therapy-Resistant Basal Cell Carcinoma Patients React Positively to New Treatment

Immunotherapy found to be effective for the treatment of basal cell carcinoma skin cancer

Basal cell carcinoma (BCC) is a type of cancer that most often develops on areas of skin exposed to the sun, such as the face, and is the most common form of skin cancer. Traditionally, BCC is treated with surgery to remove the malignant tissue. When the type of the tumor does not allow for surgery, doctors often employ biological drugs. However, the latter can cause severe side effects.

Highly effective, and with fewer side effects compared to other BCC immunotherapy drugs, Cemiplimab offers new hope for patients. A PD-1 inhibitor, Cemiplimab blocks the activity of certain checkpoint proteins that tend to be present on the surface of cells and signal immune cells not to attack.

According to a recent study by Sheba Medical Center, Cemiplimab is highly effective in treating BCC, as the tumor shrunk significantly in 30 percent of participants, while 60 percent experienced some reduction in size or a halt in development. These patients either did not react to standard biological treatments or experienced severe side effects.

Sheba Leverages ChatGPT
Accelerating Diagnostics: ChatGPT Results Aligned with Breast Cancer Board Recommendations
Recently, several distinguished Sheba clinicians were impressed by the tool’s capabilities. The group, which included Dr. Vera Sorin, Dr. Eyal Klang, Dr. Miri Sklair-Levy, Prof.…
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Sheba and Vidac
Novel Drug Set to Improve CAR T-Cell Therapy Effectiveness
While many medical centers around the world depend on external labs to genetically engineer patient T-cells, a process that can take up to a few…
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Sheba Named Global Oncology Leader
by Newsweek Magazine
Dedicated to providing those in need across the globe ‘Hope Without Boundaries,’ Sheba treats patients from more than 100 countries each year, employing the latest…
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