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Metastatic Breast Cancer Treatment in Israel

The Benefits of Metastatic Breast Cancer Treatment in Israel: Read About the Latest Advances and Uncover a First-Hand Survivor’s Account

Breasts are made of many different types of tissue, including fatty tissue, glands, ducts, lobes, lobules, and lymph nodes. Breast cancer occurs when abnormal cells in the breast begin to grow and divide uncontrollably and eventually form a tumor.

About 80% of all breast cancer cases begin in the milk ducts (ductal carcinoma), and about 10% of cases originate in the glands or lobes that produce milk (lobular carcinoma). Breast cancer is the world’s most prevalent type of cancer, and in 2020 alone 2.3 million women were diagnosed with the malignancy, which also caused 685,000 deaths globally.


To help determine the prognosis and choose the best course of treatment, breast cancer cases are delineated into stages on a scale of 0 through IV. The stage of the malignancy is determined by the cancer’s characteristics, such as how large it is and whether or not it has hormone receptors. While stage 0 describes non-invasive cancers that remain within their original location, stage IV metastatic breast cancer is an invasive form of the malignancy that has spread outside the breast to other parts of the body.

In most cases, when not detected or left untreated, breast cancer becomes invasive and spreads through the lining of the milk ducts into the surrounding breast tissue, which complicates treatment. In contrast, when the malignancy remains local and is detected early, the success rate of treatment is exceedingly high.

While about 1 in 8 women worldwide develops breast cancer at one point in their lives, the fatality rates of the disease have been dropping steadily for the past 30 years. The driving force behind this positive trend is precise early screening techniques and innovative treatments.

At Sheba Medical Cancer Center, we make the latest mammography tools available to our patients as part of metastatic breast cancer treatment, and use state-of-the-art imaging and other diagnostic techniques to find and classify the malignancy before it can spread.

A metastatic breast cancer treatment plan can include surgery, chemotherapy, targeted therapy, hormone therapy, and radiation therapy.

Targeted Therapy for Metastatic Breast Cancer Treatment

In recent years, medical research has shed light on some of the main differences between normal cells and cancer cells. These differences, or mutations, cause the latter to grow and spread out of control. This information led to the development of specialized drugs that can precisely identify and attack specific types of cancer cells. When it comes to breast cancer, advanced imaging technology, available in leading medical institutions, can dramatically enhance precise diagnostic capabilities and facilitate the application of tailored lines of treatment using targeted drugs.

Targeted therapy, officially classified as biological treatment, and also known as targeted chemotherapy, is a type of cancer treatment that uses these specialized drugs that target cancer cells while leaving healthy cells alone. Targeted therapy destroys cancer cells by blocking chemical signals that tell them to grow; changing proteins within the cells so they die; preventing new blood vessels from forming that would otherwise feed cancer cells; triggering the immune system to kill cancer cells; or sending toxins to the cancer cells to destroy them. Since these specialized drugs are made to only target specific cancer cells, targeted drugs can, in many cases, be more effective than chemotherapy, and they often have fewer side effects.

As cancer treatment research continues and advances, new and better targeted therapies are constantly being engineered. At Sheba, our skilled scientists and oncologists lead the way in the clinical application of cutting-edge targeted treatments.

Yana: The Story of a Breast Cancer Survivor

At 28 years old, Yana was pregnant with her first child and diagnosed with breast cancer. Her treatment program at Sheba Medical Center was complex and comprehensive, including targeted chemotherapy, radiation, a total mastectomy, and breast reconstruction surgery. She asserts that at every step of her long journey, she felt confident that she was in the best medical hands. Since her recovery, Yana has given birth to a second daughter. To learn more about Yana’s battle with cancer and treatment at Sheba.

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Reasons to Choose Israel for Metastatic Breast Cancer Treatment

Advanced Treatment:

Medical institutions in Israel and the US often collaborate in advanced cancer research, developing new and effective treatments against the disease, yet Israel has fewer constraints than the US when it comes to adopting novel therapies. Israeli clinical trials still adhere to the highest safety standards, but innovative treatments are generally made available to patients sooner than in the US.

Quality of Care:

Israeli physicians are exceptionally well-trained and often spend even more time on their medical education than American doctors. Also, you can be assured of high standards and strict safety regulations if you choose a hospital accredited by a trustworthy authority.


In many countries, healthcare costs can be exorbitant. Without insurance, the costs of cancer treatment can be crippling. Prices are much lower in Israel, averaging 30-80% less than in the US, for example. That said, you’re not trading affordability for quality, since Israeli specialists, medical institutions, equipment, and procedures are among the most advanced in the world.

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Where to Pursue Treatment in Israel?

Having discovered a few of the many advantages of getting metastatic breast cancer treatment in Israel, where exactly should you pursue it? Sheba Medical Center is an exceptional choice. One of the 10 best hospitals in the world according to Newsweek magazine, Sheba is dedicated to providing patients with world-class medical care.

The advantages of receiving breast cancer treatment at Sheba Medical Center include:

  • Sheba sees over 4,000 breast cancer patients yearly and performed approximately 12,000 mammograms, 51,000 ultrasounds, 3,200 MRIs, and 2,500 biopsies to date: providing its physicians with vast professional experience.
  • As a government institution, we have no hidden costs, and our fees are transparent. Although we offer advanced treatments available only in select medical institutions around the world, our prices are affordable.
  • Sheba treats each patient as a unique individual, personalizing every therapy program.
  • Sheba’s 360-degree care approach to every patient means that Sheba’s professionals will assist you with arranging medical record reviews, travel, visas, accommodations, and language interpretation as needed.
  • Sheba has full accreditation from the Joint Commission International (JCI), the premier international healthcare accrediting group.
  • Sheba has both advanced treatment and laboratory facilities. At Sheba, patients receive every aspect of their treatment in a single facility.
  • Our physicians are actively involved in the latest research and application of progressive treatments.

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Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone.

We welcome all cases, including the rarest and the most challenging. Our medical teams collaborate to provide the best possible health outcomes. From your initial inquiry through the long-term follow-up care, we are here for you.

Request a consultation and a Sheba Case Manager will contact you shortly: