HIPEC Procedure in Sheba Medical Center
The HIPEC Procedure: Learn More About This Advanced Cancer Treatment
Malignancies such as gastrointestinal tumors, ovarian cancer, mesothelioma, and appendiceal cancer often metastasize, or spread to the abdominal cavity – the largest hollow space of the body that stretches from the diaphragm to the upper plane of the pelvic cavity. The abdominal cavity is lined by the peritoneum, a membrane that covers not only the inside wall of the cavity (parietal peritoneum) but also every organ in it (visceral peritoneum). The space between the visceral and parietal peritoneum is called the peritoneal cavity. Chemotherapy is usually the treatment of choice in these cases. Unfortunately, the prognosis is often bad.
The problem with conventional chemotherapy in these cases is that it is almost always administered intravenously, while many of these cancers have poor blood circulation, meaning it is difficult for the chemotherapy drugs to reach their targets via the circulatory system.

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