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Diagnosing Pediatric Germ Cell Tumors

The first step of diagnostic evaluation involves performing a physical examination and taking a careful medical history. This is generally followed by various procedures, depending on the particular symptoms:

  • CT scan of chest, abdomen and pelvis, with oral and intravenous contrast
  • Ultrasound of testes (if it is a testicular tumor) or abdomen (if it is an ovarian tumor)
  • Blood tests for AFP and bHCG (these levels are elevated in some germ cell tumors)
  • Blood tests to measure blood counts and liver and kidney functions
  • Baseline hearing evaluation
  • Pulmonary function tests for lung evaluation
  • Nuclear medicine GFR test for kidney assessment

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