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Acute Myeloid Leukemia Treatment

At Sheba Medical Center, a highly respected team of multidisciplinary specialists will collaborate to ensure that you benefit from the most progressive and personalized treatments for acute myeloid leukemia. Your treatment options may be determined based on the type of AML, your age, and your general state of health, among other factors. Medical oncologists, hematologists, and radiation oncologists will combine their experience and knowledge to design your integrative therapies.

Treatment options at Sheba include:


Chemotherapy is the primary treatment for most adults with AML, and it is generally divided into phases. The first phase is Induction, and it is short and intensive – with the goal of killing as many leukemia cells as possible to lead to remission. The second phase is Consolidation (post-remission), and it works to destroy the remaining inactive cancer cells.

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Targeted Therapy

New drugs that identify and target specific parts of leukemia cells without harming normal cells have been developed in recent years. Targeted therapy has been shown to be effective in treating certain types of AML. Examples of oral targeted agents that may be prescribed for AML include midostaurin, gilteritinib, IDH inhibitors (ivosidenib, enasidenib), and glasdegib.

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Bone Marrow/Stem Cell Transplant

A bone marrow/stem cell transplant can be used as part of initial treatment for AML or part of treatment for disease relapse. This procedure replaces bone marrow damaged by leukemia with highly specialized stem cells that multiply and develop into healthy bone marrow. There are two types of stem cell transplants – allogeneic transplants that use donated stem cells, and autologous transplants that use the patient’s own stem cells.

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Radiation Therapy

Radiation therapy applies high-energy x-rays to kill cancer cells. This treatment is not typically part of the primary treatment for AML, but it may be helpful for treating leukemia that has spread, or to shrink a tumor.

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Treatments that Take Care of Your Whole Body

Throughout the entire course of your treatment at Sheba Medical Center, we will stay focused on your overall quality of life. We aim to make your therapy as efficient and comfortable as possible. To that end, we offer a full range of support services – including social workers, alternative therapies, and nutritional counseling – to ensure that all of your individual needs are met as you cope with cancer.

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Sheba Medical Center provides innovative, personalized medical care to patients from around the world. We are the largest, most comprehensive hospital in the Middle East and dedicated to providing advanced and compassionate medicine for everyone. We welcome all cases, including the rarest and the most challenging. Our medical teams collaborate to provide the best possible health outcomes. From your initial inquiry through the long-term follow-up care, we are here for you.

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