CAR-T treatment for leukemia is an innovative process that uses your own immune cells to seek and destroy cancerous cells.
After some blood is taken from the patient, the T-cells, a type of immune cell, are removed from the sample. Using advanced genetic engineering techniques, the T-cells are modified, causing them to create chimeric antigen receptors (CARs). These CARs program the T-cells to find and destroy cancer cells when injected back into the patient.
The patient receives chemotherapy while the modified T-cells grow in our laboratory. The chemotherapy dampens the patient’s immune system, permitting the CAR T-cells to do a better job of eliminating malignant cells.
Cancer Cell
Engineered T-Cells
CAR-T therapy is limited to patients under 50 years of age because of possible side effects. Additionally, potential patients need to have undergone at least two prior leukemia treatments. The CAR-T protocol requires hospitalization of at least two weeks, but same patients may need a longer observation period.
Great success has been achieved in young patients with CAR-T treatment. The following are the rates of complete recovery with this therapy:
Of course, Sheba continues to strive to further improve these rates through continuous research and retaining the best physicians.
If you have a loved one suffering from leukemia, contact us right away. We’ll be happy to answer all your questions and help in every possible way.
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Established in 1948, Sheba Medical Center is now the leading medical center in the region.
