CAR T-cell Therapy for Multiple Myeloma at Sheba Medical Center
Previously offered only to patients with leukemia or lymphoma, CAR T-cell therapy is now available at Sheba as a treatment for multiple myeloma.

A New Treatment for Multiple Myeloma at Sheba
Until recently, Sheba offered CAR T-cell therapy for patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin’s lymphoma.
Following recent FDA approval, we are pleased to announce that CAR T-cell therapy for multiple myeloma (MM) is now available for patients battling the malignancy.
Commenting on the addition of CAR T-cell therapy to the multiple myeloma therapeutic arsenal, Director of the Multiple Myeloma Unit at Sheba, Dr. Hila Magen, explained: “We are talking about an advanced immunotherapy that ‘re-educates’ the patient’s immune system to fight cancerous myeloma cells. It is truly an incredible breakthrough that opens the door for new multiple myeloma therapeutic approaches.”
The number of adults who have undergone this therapy CAR T-cell therapy at Sheba:

Why Chose Sheba for CAR T-cell Therapy
Unparalleled Experience
Sheba’s extensive experience with CAR T-cell therapy speaks louder than words. Led by Prof. Arnon Nagler, President of the Hemato-Oncology Center and a world-renowned specialist in the field, we have provided over 220 patients with CAR-T therapy, including about 60 children.
Efficient, Comfortable, and Patient-Centric Experience
CAR-T therapy at Sheba is all-inclusive. That means all stages of the process are done on campus, including blood harvesting, genetic engineering of the cells, T-cell injections, and patient observation. The patient experience is therefore as convenient and comfortable as possible.
Fast Availability of CARs
CARs are more readily available at Sheba because the cells are engineered at an on-site laboratory, a process that only takes about 10 days to complete. In contrast, other medical centers use commercial CARs that must be shipped overseas for engineering, so the entire process, from lymphocyte collection to delivery, can take weeks or even months. The extra wait-time not only gives the disease time to progress, but also reduces the chances of a positive patient response to the CARs.
World-renowned Experts
The physicians at Sheba are some of the most experienced in the world in the field of CAR-T therapy. Prof. Nagler, a renowned expert on the topic, is one of the three board members of the organizing committee for the largest European conference held annually on CAR T-cell therapy.

Sheba Medical Center A Leader in Medicine and Biotechnological Innovation

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